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Updated: Jul 6, 2025

Intracellular Refolding Assay
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热冲击因子1直接调节转硫路径,促进前列腺癌的扩散和存活率

J Spencer Hauck1, David Moon1, Xue Jiang1

  • 1Department of Pathology and Duke Cancer Institute, Duke University School of Medicine, Room 301M, Duke South DUMC 3712, 40 Duke Medicine Circle, Durham, NC, 27710, USA.

Communications biology
|January 3, 2024
PubMed
概括

热冲击因子1 (HSF1) 针对晚期前列腺癌 (PCa) 中的囊氨酸β合成酶 (CBS). 抑制HSF1和CBS有效地减少PCa生长和瘤细胞死亡,提供了一个新的治疗策略.

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