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Updated: Jul 6, 2025

Single Molecule Fluorescence Energy Transfer Study of Ribosome Protein Synthesis
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eRF1降解剂SRI-41315在核糖体解码中心起到分子的作用

João P L Coelho1, Matthew C J Yip1, Keely Oltion2

  • 1Department of Cell Biology, Harvard Medical School, Boston, MA, USA.

Nature chemical biology
|January 3, 2024
PubMed
概括

小分子SRI-41315将eRF1与核糖体结合,导致碰撞并增强翻译终止. 这揭示了针对 eRF1 的新方法,用于与过早停止密码子相关的疾病.

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