PDE4D单核酸多态性rs918592与缺血有关 中国人群中风风险:元分析
Xinrui Yu1, Guiying Zhang1, Xuelei Tang1
1Department of Biology, Hainan Medical University, Haikou, China.
BMC cardiovascular disorders
|January 3, 2024
概括
这一元分析发现,在中国人群中,基酶4D (PDE4D) 单核酸多态化 (SNP) rs918592和缺血性中风 (IS) 风险之间存在显著联系. G基因组与发展IS的风险降低有关.
科学领域:
- 遗传学和分子生物学
- 神经科学是一个神经科学.
- 心血管研究研究心血管研究
背景情况:
- 关于中国人群中基酶4D (PDE4D) 单核酸多态 (SNP) rs918592和缺血性中风 (IS) 风险之间的关联存在不一致的发现.
- 进行了一项元分析,以澄清PDE4D SNP rs918592和IS风险之间的关系.
结论:
- 在PDE4D中SNP rs918592是中国人群中IS风险的潜在贡献者.
- 这项研究提供了关于PDE4D SNP rs918592和IS风险在这个人口群体之间的关联的最终答案.
- 功能分析表明rs918592及其相关的SNP可能具有影响IS风险的监管功能.
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