接受腹腔营养的新生儿的治疗相关问题:风险因素和对实践的影响
Amal Akour1,2, Lobna Gharaibeh3, Omar El Khatib4
1Department of Pharmacology and Therapeutics, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, UAE. aakour@uaeu.ac.ae.
BMC pediatrics
|January 3, 2024
概括
新生儿亲肠营养 (PN) 中与治疗相关的问题 (TRPs) 通常源于药物监测和剂量问题. 解决这些药物治疗因素是预防接受PN新生儿并发症的关键.
科学领域:
- 新生儿护理 新生儿护理
- 临床药房 临床药房 临床药房
- 父母肠道营养是一种营养.
背景情况:
- 亲肠道营养 (PN) 对新生儿至关重要,但可能导致与治疗有关的问题 (TRPs).
- 了解TRP及其促成因素对于预防新生儿患者的不良结果至关重要.
研究的目的:
- 评估影响治疗相关问题 (TRPs) 的因素,新生儿接受亲肠营养 (PN) 的新生儿患者.
主要方法:
- 对接受PN的96名新生儿进行了回顾性图表审查.
- 收集的数据包括人口统计,实验室结果和与PN和药物治疗相关的TRP.
主要成果:
- 与药物治疗有关的最常见的TRP是缺乏监测 (34.2%) 和低剂量 (17.5%).
- 三分之一的患者在营养需求和PN组成之间存在不匹配.
- 在药物数量和TRP之间发现了正相关性 (r=0.275,p<0.01;r=0.532,p<0.001).
结论:
- 新生儿PN中TRPs很常见,主要与药物治疗问题,如监测和剂量有关.
- 鉴定TRP的风险因素强调了临床药剂师在预防策略中的重要性.
相关概念视频
Parentral Nutrition: Centeral and Peripheral Parental Nutrition
165
Parenteral Nutrition (PN) delivers essential nutrients directly into the bloodstream, bypassing the digestive system. It is commonly used for individuals with severe digestive disorders or conditions that prevent normal nutrient absorption.
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
165
Enteral Nutrition I: Orogastric and Nasogastric Feeding
292
Enteral nutrition delivers nutrients directly to the stomach or small intestine through a tube. This method is appropriate for patients who cannot eat but still have a functioning digestive system. It is also beneficial for individuals with swallowing difficulties, anorexia, malabsorption, or those who have undergone gastrointestinal (GI) surgery.
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...
Orogastric (OG) and nasogastric (NG) feeding are two standard methods used for enteral nutrition. Enteral nutrition is often preferred over...
292
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding
152
Enteral nutrition encompasses various methods of delivering nutrition directly to the gastrointestinal (GI) tract, bypassing traditional oral intake. It is particularly beneficial for patients who cannot eat by mouth but have a functioning digestive system. Key methods include nasointestinal feeding, gastrostomy, and jejunostomy, each suited to different clinical scenarios based on the patient's needs and condition.
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
152
Factors Affecting Drug Response: Overview
2.0K
When it comes to infants and young children, they are typically administered smaller doses of medication in comparison to adults. This is primarily because their organ functions still need to fully develop, meaning their bodies are not as efficient at metabolizing or eliminating drugs. Additionally, their blood-brain barrier is more permeable than in adults. As a result, high concentrations of drugs can easily penetrate the central nervous system (CNS), potentially leading to neurological...
2.0K
Pneumonia V: Nursing management and Prevention
2.1K
Nursing management of pneumonia involves promoting airway patency, facilitating rest and conserving energy, encouraging fluid intake, maintaining nutrition, and educating patients.
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
2.1K
Factors Affecting Protein-Drug Binding: Patient-Related Factors
61
Protein-drug binding, a pivotal aspect of pharmacokinetics, is subject to considerable variability influenced by an array of patient-related factors. The intricate interplay of age, individual differences, and pathological conditions significantly impact the binding dynamics and subsequent pharmacological effects.
Age stands as a key determinant in protein-drug binding. Neonates, characterized by low albumin content, experience heightened concentrations of unbound drugs such as phenytoin and...
Age stands as a key determinant in protein-drug binding. Neonates, characterized by low albumin content, experience heightened concentrations of unbound drugs such as phenytoin and...
61


