鱼雷黄斑病的长期随访:一个病例系列和迷你审查
Richard C Trevino1, William H Ridder2, Anupam Laul3
1School of Optometry, Indiana University, 800 Atwater Ave Bloomington, Bloomington, IN, 47405, USA. rctrevin@iu.edu.
BMC ophthalmology
|January 3, 2024
概括
鱼雷黄斑病 (TM) 是一种罕见的先天性疾病. 这项为期10年的随访研究显示,在大多数情况下,视觉功能和病变形态都稳定,这表明TM通常是不渐进的.
科学领域:
- 眼科医生 眼科 眼科
- 遗传学 遗传学 是一个
- 视网膜疾病 视网膜疾病
背景情况:
- 鱼雷黄斑病 (TM) 是一种罕见的先天性疾病,影响着斑点.
- TM 的病因仍然是未知的.
- 对于TM,长期随访数据有限.
研究的目的:
- 为了描述鱼雷黄斑病的长期自然史.
- 报告两名患有TM的患者10年的随访情况.
- 评估TM中视觉功能和病变形态的稳定性.
主要方法:
- 长度研究,随访10年.
- 眼科检查包括 fundus 摄影,周边测量,自发光和OCT.
- 在一个患者中对APC基因的基因分析.
主要成果:
- 视觉功能在10年内在两名患者中保持稳定.
- 病例1显示病变形态没有变化.
- 病例2在病变内表现出囊性退行症的进展.
- 在案例1中的基因分析没有揭示与加德纳综合征相关的显著变异.
结论:
- 鱼雷黄斑病似乎是一个不进展的疾病,具有长期的视觉稳定性.
- 这些发现不支持在报告的病例中TM和加德纳综合征之间的关联.
更多相关视频
相关概念视频
Glaucoma: Overview
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Open Angle Glaucoma: Treatment
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...


