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在工程外体中封装和评估治疗载荷:系统性审查

Zhen Chen^1,2,3, Min Xiong⁴, Jiaqi Tian^1,2

¹Clinical Medical Research Center for Women and Children Diseases, Key Laboratory of Birth Regulation and Control Technology of National Health Commission of China, Shandong Provincial Maternal and Child Health Care Hospital Affiliated to Qingdao University, Jinan, 250001, China.

Journal of nanobiotechnology

|January 3, 2024

概括

工程外体显示出对各种疾病的治疗潜力. 本综述详细介绍了优化外体体药物加载,递送和临床转换以获得增强疗法的方法.

科学领域:

生物技术和纳米医学
细胞生物学和治疗学

背景情况:

外体是纳米级囊泡,对癌症,心血管,神经和免疫疾病具有治疗潜力.
目前在优化药物加载和评估工程外体在药物输送方面的有效性方面存在知识差距.

结论:

为合理设计和严格评估外体细胞作为治疗药物的系统框架提供.
鉴定方法和报告标准的进步对于加速基于外体细胞的治疗开发至关重要.
进一步的研究和开发将促进对各种疾病的工程外体的临床应用.

关键词:

临床翻译临床翻译药物封装的药物封装.评估有效性的评估.工程外生体的工程外生体.

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