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Updated: Jul 6, 2025

Author Spotlight: Establishing MASLD Cell Models for Investigating Disease Mechanisms and the Lipid-Lowering Effects of Koumiss
07:03

Author Spotlight: Establishing MASLD Cell Models for Investigating Disease Mechanisms and the Lipid-Lowering Effects of Koumiss

Published on: July 19, 2024

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费诺纤维酸通过增强PPARα/PGC-1α信号通路合线粒体功能来缓解NAFLD

Xuemei Wang1, Jieying Wang1, Cao Ying1

  • 1Department of public health, Xi'an Medical College, No. 1 Xinwang Road, Weiyang District, Xi'an, Shaanxi, 710000, China.

BMC pharmacology & toxicology
|January 4, 2024
PubMed
概括

费诺纤维酸治疗通过增强线粒体功能和减少肝脂积累,改善了小鼠的非酒精性脂肪性肝病 (NAFLD). 过度表达PGC-1α也减轻了肝细胞中的脂质沉积和氧化应激.

关键词:
菲诺纤维酸盐的使用方法脂质的积累 脂质的积累线粒体的功能非酒精性脂肪性肝病是非酒精性脂肪性肝病.过氧体增殖器激活受体玛联合激活剂1α.

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