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聚乳-合-甘油酸 (PLGA) 纳米颗粒和通过皮肤递送药物:一个概述

Lalit Kumar¹, Gauree Kukreti², Ritesh Rana³

¹Department of Pharmaceutics, GNA School of Pharmacy, GNA University, Phagwara, Punjab 144401, India.

Current pharmaceutical design

|January 4, 2024

概括

[PLGA]纳米颗粒显示出通过皮肤递送药物的前景,比传统方法提供优势. 需要进一步的临床研究来克服应用中的挑战.

科学领域:

制药纳米技术制药纳米技术
生物材料科学生物材料科学

背景情况:

可生物降解的聚合物,特别是Poly (乳酸-co-甘油酸) [PLGA],在制药行业越来越重要,用于纳米颗粒配方.
PLGA的多功能性支持纳米颗粒制备用于各种管理路径,包括静脉注射和透皮.
基于纳米颗粒的药物输送系统是提高治疗效率和患者服药的关键重点.

结论:

PLGA纳米颗粒代表了通过皮肤递送药物的有希望的平台.
尽管临床前取得了成功,但在通过皮肤治疗中对PLGA纳米颗粒的临床转化仍然存在重大障碍.
持续的研究对于充分实现PLGA纳米颗粒在临床透皮药物递送中的潜力至关重要.

关键词:

它是生物降解的.在 PLGA PLGA 中.剂量频率剂量的频率纳米颗粒是一种纳米粒子.在临床前的临床前.通过皮肤.

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