在头部和部光免疫疗法后,有两例紧急气管切除术
Isaku Okamoto1, Takuro Okada1, Kunihiko Tokashiki1
1Department of Otorhinolaryngology, Head and Neck Surgery, Tokyo Medical University, Tokyo, Japan.
Cancer diagnosis & prognosis
|January 4, 2024
概括
头部和部光免疫疗法 (HN-PIT) 是一种不断增长的治疗方法,但喉胀仍然是一个风险. 由于这种并发症,两名患者需要紧急气管切除术,这凸显了关于预防措施的仔细患者同意的必要性.
科学领域:
- 在瘤学瘤学.
- 光动力学疗法 光动力学疗法
- 头部和部癌症 治疗 治疗
背景情况:
- 头部和部光免疫疗法 (HN-PIT) 在日本已经成为保险治疗方法三年了,已经进行了350多例.
- 尽管它的使用越来越多,但喉胀等临床挑战仍然存在.
- 预防性或紧急气管切除术的同意对于接受HN-PIT的患者至关重要.
研究的目的:
- 报告HN-PIT后出现的两个喉 edem 的病例.
- 强调在HN-PIT患者中考虑气管切除术的重要性.
- 为了突出HN-PIT协议的不断改进的需要.
主要方法:
- 对23名患者的44个HN-PIT周期的回顾性审查 (2021年1月 - 2023年10月).
- 详细报道了两起由于喉胀而需要紧急气管切除术的病例.
- 描述HN-PIT在头癌复发中的应用.
主要成果:
- 两名患者在HN-PIT后出现了严重的喉胀,尽管最初的风险评估很低.
- 这两位患者都需要紧急气管切除术.
- 这些病例发生在患有复发性下牙癌和中喉癌的患者中.
结论:
- HN-PIT治疗仍在发展,需要进一步标准化.
- 喉 edem 是 HN-PIT 的一个显著的潜在并发症.
- 仔细的患者咨询和考虑气管切除术对于管理HN-PIT风险至关重要.
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