用电子医疗记录 (EMR) 数据库识别对脊髓损伤 (SCI) 队列的初级保健抗生素处方模式
Arrani Senthinathan1,2, Melanie Penner3,4, Karen Tu5,6,7
1Institute of Health Policy Management and Evaluation, University of Toronto, Toronto, ON, Canada.
Topics in spinal cord injury rehabilitation
|January 4, 2024
概括
脊髓损伤 (SCI) 的成年人经常使用抗生素,主要用于尿路感染 (UTI). 导管使用增加了抗生素处方,而医生的经验影响了处方持续时间.
科学领域:
- 传染性疾病 传染性疾病
- 腎臟病學 (nephrology) 是一種醫學專業.
- 神经学 神经学
- 公共卫生 公共卫生
- 药理学 药理学是指药理学的学科.
背景情况:
- 脊髓损伤 (SCI) 种群的抗生素利用率很高.
- 有限的研究存在于SCI成年人的门诊抗生素处方模式.
- 了解这些模式对于优化抗菌药物管理至关重要.
研究的目的:
- 描述SCI成年人的初级保健抗生素处方.
- 确定与抗生素处方频率和持续时间相关的患者和初级保健医生 (PCP) 相关因素.
主要方法:
- 使用链接健康行政和电子医疗记录 (EMR) 的回顾性队列研究.
- 2013年至2015年间,从加拿大安大略省432名患有SCI的成年人中收集的数据.
- 使用负二项式回归分析来确定相关因素.
主要成果:
- 61.1%的SCI队列从他们的PCP获得了至少一个抗生素处方.
- 尿路感染 (UTI) 占处方的59.8%;诺是处方最多的类 (24.6%).
- 导管的使用显著增加了抗生素处方的数量 (RR=3.1),而职业生涯末期的PCP处方时间更长 (RR=1.8).
结论:
- 尿路感染 (UTI) 是SCI患者使用抗生素的首要指示.
- 导管使用和PCP职业生涯阶段是影响这种人群抗生素处方的重要因素.
- 这些发现凸显了针对SCI患者的针对性抗微生物管理干预措施的必要性.
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