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在第二次脏移植中预测移植功能和存活率的预测因素:一个单一中心的经验
Mahmoud Khalil1, Rabea Ahmed Gadelkareem2, Medhat Ahmed Abdallah1
1Department of Urology, Assiut Urology and Nephrology Hospital, Faculty of Medicine, Assiut University, Assiut 71515, Assiut, Egypt.
World journal of transplantation
|January 4, 2024
概括
在第一次或第二次移植中,移植功能的延迟会对第二次移植的存活率产生负面影响. 然而,第二次脏移植的存活率与第一次脏移植相当.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 移植手术 移植手术
- 免疫学 免疫学 免疫学
背景情况:
- 脏再移植越来越常见,需要对其风险因素和结果进行研究.
- 了解各个移植中心的经验,可以增强关于移植的文献.
研究的目的:
- 确定影响初级移植功能和第二次移植 (SKT) 后移植存活率的风险因素.
主要方法:
- 在1977年至2014年期间在欧洲第三级医疗中心进行的48起SKT病例的回顾性分析.
- 卡普兰-梅尔曲线用于描述患者和移植的生存率.
- 两变量分析评估了预测因素和结果之间的关联.
主要成果:
- 由于急性排斥而导致的高BMI和第一个移植损失预测了第二个移植的初级非功能 (PNF).
- 在第一次或第二次移植中延迟的移植功能显著降低了第二次移植的存活率.
- 10年患者和移植的生存率分别为83.0%和51.6%.
结论:
- 在第一次或第二次移植中延迟的移植功能与SKT的较差结果有关.
- 对于SKT,患者和移植的存活率与第一次脏移植的存活率相似.
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