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针对副甲状腺瘤的手术前局部化进行侵入性检测

Akua Graf¹, Craig Cochran¹, Samira Sadowski²

¹National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

Journal of the Endocrine Society

|January 4, 2024

概括

选择性动脉低血刺激精确地定位了持续性原发性甲状腺功能障碍症 (PHPT) 病例中的副甲状腺瘤. 这种侵入性技术可以指导重复手术,并可能消除选择性静脉采样 (SVS) 的需要.

科学领域:

内分泌学在内分泌学.
手术瘤学手术瘤学
放射学放射学是一门学科.

背景情况:

准确的副甲状腺瘤定位对于在持久/复发性原发性副甲状腺瘤 (PHPT) 中成功进行重复手术至关重要.
非侵入性成像可能会失败,需要进行侵入性手术,如动脉造影和选择性静脉采样 (SVS).

研究的目的:

评估侵袭性副甲状腺瘤局部化技术的经验.
提出对选择性动脉低热血刺激的随访数据,用于甲状腺瘤局部化的中央静脉采样.

主要方法:

对94名接受甲状腺瘤局部化手术前侵入性检测 (1991-2020) 的患者的回顾性分析.
侵入性研究包括动脉图,低热血刺激和选择性静脉采样 (SVS).
结果根据组织学和生物化学结果被分类为真阳性,假阳性或假阴性.

主要成果:

与动脉图 (50%) 相比,选择性动脉低热血刺激的准确性更高 (60%).
选择性静脉采样 (SVS) 在定位副甲状腺瘤方面取得了82%的准确性.
当与阳性动脉图红色相结合时,低热血刺激的准确性更高 (74%对44%).

结论:

选择性动脉低血刺激是PHPT中侵入性副甲状腺瘤局部化的一个有价值的辅助.
这种技术有可能消除选择性静脉采样 (SVS) 的需要,简化了手术规划.

关键词:

18F-FCH 聚乙烯/聚乙烯/聚乙烯动脉图 (arteriogram) 是一个动脉图.低热血性刺激的低热血性刺激副甲状腺重新操作静脉采样静脉采样

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