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脑卒中发生率的年龄依赖性季节性:一项为期21年的基于人口的研究

Carmit Libruder¹, Rami Yaari², Ronen Fluss²

¹Israel Center for Disease Control, Israel Ministry of Health, Ramat Gan, Tel Hashomer, Israel.

European stroke journal

|January 4, 2024

概括

脑卒中发生率呈现季节性模式,因年龄而异. 年轻人在夏季更容易中风,而老年人在冬季更容易中风,特别是脑内出血.

科学领域:

神经学神经学
流行病学流行病学
公共卫生公共卫生

背景情况:

记录了中风发病率的季节性变化,但特定年龄的差异仍未得到充分探索.
了解与年龄相关的季节性对于有针对性的公共卫生干预和临床监测至关重要.

研究的目的:

调查依赖年龄的季节性缺血性中风 (IS),短暂缺血性攻击 (TIA) 和脑内出血 (ICH) 的发生率.
在不同类型的中风中识别不同的季节性模式及其与年龄的关系.

主要方法:

利用了大规模的以色列数据集 (2000-2020年),包括IS/TIA和ICH住院.
分层数据分为五个年龄组 (18-49岁,50-59岁,60-69岁,70-79岁,80岁以上).
采用了通用添加模型来分析每月发病率,并使用速率比率 (RRs) 来量化季节性影响.

主要成果:

确定了IS/TIA的年龄和季节性之间的显著相互作用,并观察到相位转移.
年轻人 (70岁以下) 显示夏季峰值,较年轻年龄组的RR更高 (18-49岁组的RR峰值为1.11).
老年人 (80岁以上) 冬季出现IS/TIA (峰值RR1.07) 和ICH (峰值RR1.20) 的峰值,随着年龄的增长,RR增加.

结论:

脑卒中发病率表现出特定年龄的季节性模式,需要定制的监测策略.
老年人,特别是在冬季,需要对心血管风险因素进行更密切的监测.
需要进一步的研究来阐明与年龄相关的中风发病率季节性相位变化背后的机制.

关键词:

一次性中风,中风.缺血性中风中风季节性变化的季节性变化.季节性的季节性.过渡性缺血性攻击是短暂的

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