在智利的狗中首次检测到Omicron变异BA.4.1血统,智利
B Agüero1,2, F Berrios2, C Pardo-Roa3,4
1Programa de Doctorado en Ciencias Silvoagropecuarias y Veterinarias, Universidad de Chile, Santiago, Chile.
The veterinary quarterly
|January 4, 2024
概括
在智利,有三只狗感染了SARS-CoV-2,这是全球首次报告的物携带Omicron BA.4.1变种. 人类疫苗接种率高可能导致物感染率低.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 传染性疾病 传染性疾病
- 基因组学就是基因组学.
背景情况:
- 由SARS-CoV-2引起的COVID-19大流行,引发了人们对对家禽的潜在传播的担忧.
- 关于智利境内物中SARS-CoV-2感染的数据有限,需要进一步调查.
- 众所周知,狗和猫很容易感染SARS-CoV-2病毒.
研究的目的:
- 在智利的家养狗和猫中调查SARS-CoV-2的流行情况.
- 在感染的物中识别SARS-CoV-2变种并了解传播动态.
- 评估疫情期间物在"一健康"框架中的作用.
主要方法:
- 在COVID-19阳性家庭65只物鼻腔,便和环境样本的RT-PCR分析.
- 测试了700个来自未知COVID-19状况的家庭动物的鼻子抽样.
- 检测到的SARS-CoV-2菌株的全基因组测序和遗传学分析.
主要成果:
- 在65只COVID-19阳性家庭中的3只物 (4.6%) 中检测到了SARS-CoV-2,这表明人与物的传播.
- 在未知COVID-19状态的家庭的物中没有发现SARS-CoV-2感染.
- 感染狗的两个SARS-CoV-2基因组属于Omicron BA.4.1变种,这是全球首次在动物中报告的,与智利的人类序列聚集在一起.
结论:
- 该研究发现,智利物中SARS-CoV-2的流行率较低,有证据表明Omicron BA.4.1变种的人对物传播.
- 智利的人类疫苗接种率高可能导致SARS-CoV-2在物中的有限传播.
- 加强人类疫苗接种和采用"一个健康"的方法对于管理动物传播疾病风险和物种间传播至关重要.
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