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Updated: Jul 6, 2025

Analyzing Protein Dynamics Using Hydrogen Exchange Mass Spectrometry
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Published on: November 29, 2013

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在复杂分子中计算原子转移激活屏障的坚固的基于碎片的方法

Yizhou Liu1, Frank C Pickard2,3, Gregory W Sluggett1

  • 1Analytical Research and Development, Pfizer Research and Development, 445 Eastern Point Road, Groton, CT 06340, USA. Yizhou.Liu@pfizer.com.

Physical chemistry chemical physics : PCCP
|January 4, 2024
PubMed
概括

非共价相互作用显著影响复杂分子的反应速率,如活性药物成分 (API). 考虑结构灵活性和多个路径对于准确的激活能计算至关重要.

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