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虚拟非对比系列的光子计数探测器计算机断层扫描血管造影对大动脉的度评分

Franka Risch¹, Eva Harmel², Katharina Rippel¹

¹Department of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Augsburg, Stenglinstr. 2, 86156, Augsburg, Germany.

The international journal of cardiovascular imaging

|January 4, 2024

概括

光子计数探测器CT上的虚拟非对比 (VNC) 算法有效地消除了对比度,并将噪声水平与真正的非对比度扫描相匹配. 虽然大动脉的评分是可行的,但与真正的非对比扫描相比,VNC算法显示了显著的低估.

科学领域:

医疗成像医学成像
放射学放射学是一门学科.
光子计数探测器CT CT

背景情况:

光子计数检测器CT (PCD-CT) 提供了先进的成像功能.
虚拟非对比 (VNC) 成像旨在通过消除单独的真非对比 (TNC) 扫描的需要来减少辐射剂量和扫描时间.
准确评估大动脉的 (AVC) 对于TAVR规划至关重要.

研究的目的:

在PCD-CT数据上评估两个VNC算法 (传统和保存).
将VNC算法与真非对比 (TNC) 扫描进行噪声水平,对比介质减去效率和AVC评分的比较.
确定VNC作为TAVR规划中TNC扫描的替代品的潜力.

主要方法:

从PCD-CT数据中使用常规 (VNCconv) 和保存 (VNCpc) 算法重建VNC序列.
通过左心室CT值的标准偏差分析噪声水平.
通过对心脏细分体积 (>130 HU) 的组图分析来评估对比度去除.
使用Agatston和体积得分测量AVC,比较VNC和TNC数据集.

主要成果:

所有的VNC重建都实现了与TNC扫描相匹配的噪音水平.
证明了对比介质的有效虚拟去除 (比率>130 HU从81%降至<1%).
VNCconv显著低估了AVC得分 (高达74%),而VNCpc显示了最小的差异 (中位数为29%),但仍被低估.
两种VNC算法都显示出与TNC进行AVC评分的近乎完美的相关性 (r2>0.9).

结论:

在PCD-CT上的薄切片VNC重建提供了与TNC相当的噪音,并有效地消除了对比度.
虽然近乎完美的相关性可以实现AVC评分,但仍然存在严重的低估.
特别是使用0.4毫米切片和QIR 4的Br36内核的VNCpc算法,显示出其作为额外的TNC扫描的替代方案,并进一步优化.

关键词:

大动脉膜的量化量化对敏感的算法光子计数探测器计算机断层扫描.辐射剂量降低潜力的辐射剂量降低潜力虚拟非对比的虚拟非对比

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