经过20年的努力:一个活着的脏移植接受者的耐受性
Manal Alotaibi1,2, Ziad Alahmadi3, Niraj Desai4
1Comprehensive Transplant Center and Division of Nephrology, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA. Meotaibi@hotmail.com.
Journal of nephrology
|January 4, 2024
概括
这项案例研究突出显示了移植接受者的成功免疫抑制断奶. 患者实现了功能耐受性,在共享捐赠者血液细胞移植后证明了长期移植存活.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 免疫学 免疫学 免疫学
- 血液学 血液学 血液学
背景情况:
- 接受脏移植的人通常需要终身免疫抑制以防止器官排斥,这会产生显著的不良影响.
- 一小部分患者可以在保持移植功能的同时停止免疫抑制,这种状态称为操作耐受性.
相关概念视频
Tissue Transplantation
372
Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
372
Cell-mediated Immune Responses
68.3K
Overview
68.3K
Bone Marrow Sampling and Transplants
333
Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
333


