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Updated: Jul 6, 2025

Author Spotlight: Finding New Therapeutic Targets for Malignant Peripheral Nerve Sheath Tumor Through Genome-Scale shRNA Screens
09:33

Author Spotlight: Finding New Therapeutic Targets for Malignant Peripheral Nerve Sheath Tumor Through Genome-Scale shRNA Screens

Published on: August 25, 2023

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失衡cAMP和Ras/MAPK通路作为皮肤神经纤维瘤的治疗策略

Helena Mazuelas1, Miriam Magallón-Lorenz1, Itziar Uriarte-Arrazola1

  • 1Hereditary Cancer Group, Translational Cancer Research Program, and.

JCI insight
|January 4, 2024
PubMed
概括

将MEK抑制剂与cAMP提升剂相结合,为皮肤神经纤维瘤 (cNFs) 提供了潜在的治疗方法. 这种方法永久地阻止了施万细胞的扩张,与单独使用MEK抑制剂不同,改善了NF1患者的生活质量.

关键词:
癌症 癌症 癌症 癌症细胞生物学 细胞生物学遗传性疾病是一种遗传性疾病.遗传学 遗传学 是一个瘤抑制剂 瘤抑制剂

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