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Updated: Jul 6, 2025

Detection of Copy Number Alterations Using Single Cell Sequencing
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一个统一的模型,解释了人类反转复制号变体的起源

Bonita J Brewer1, Maitreya J Dunham1, M K Raghuraman1

  • 1Department of Genome Sciences, University of Washington, Seattle, Washington, United States of America.

PLoS genetics
|January 4, 2024
PubMed
概括

一种新的机制,源依赖的反转重复放大 (ODIRA),解释了如何出现反转的结构变体和副本数变体. 这一涉及帕林德罗姆DNA的过程涉及遗传遗传性疾病和癌症.

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