耶尔西尼亚 (Yersinia enterocolitica) 生物库1A:在食物链中被低估的潜在病原体
Raphaёlle Palau1, Samuel J Bloomfield1, Claire Jenkins2
1Quadram Institute Bioscience, Norwich Research Park, Norwich, United Kingdom.
International journal of food microbiology
|January 4, 2024
概括
导致食源性疾病的Yersinia enterocolitica在英国生,猪肉和鱼中被发现. 许多隔离物与人类病例的菌株相匹配,这表明需要更多的食品监测.
科学领域:
- 食品安全 食品安全
- 微生物学 微生物学
- 基因组学就是基因组学.
背景情况:
- 耶尔西尼亚肠结肠杆菌是食物传播性胃肠炎的一个未被报告的原因.
- 关于Y. enterocolitica在食品中的多样性及其对人类疾病的贡献的知识有限.
研究的目的:
- 在英国零售食品样本中调查Yersinia enterocolitica的多样性.
- 用全基因组测序来比较食物衍生的分离物与人类衍生的菌株.
主要方法:
- 从生肉,猪肉,鱼和绿叶蔬菜中分离Y. enterocolitica.
- 207个分离物的全基因组测序 (WGS).
- 食品衍生基因组与公开可用的人类衍生基因组的比较.
主要成果:
- 在37/50的生,8/10的猪肉,8/10的鱼和1/10的绿叶样本中检测到Y. enterocolitica.
- 207个分离物属于38个序列类型 (ST);在单个样本中发现多达5个ST.
- 51%的食品样本含有与之前在英国人类病例中发现的STs相匹配的STs分离物.
- 所有分析的分离物属于生物型1A,此前被认为是非致病的.
结论:
- 生肉,猪肉和鱼是英国零售环境中Yersinia enterocolitica的重要来源.
- 食品中与人类相匹配的STs的存在突出显示了潜在的传播途径.
- 对生物型1A在人类中的致病潜力进行重新评估是有必要的.
- 广泛的食品监测对于确定Y. enterocolitica感染的来源至关重要.
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