类固醇类固醇对COVID-19的影响
Khaja Moinuddin Shaik1, Vijay Patibandla1, Sukhendu Nandi1
1Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research (NIPER), Sector 67, S.A.S. Nagar, 160062, Punjab, India.
Steroids
|January 4, 2024
概括
类固醇类固醇 (AAS) 可能会对免疫健康产生负面影响,可能会使COVID-19患者的结果恶化. 需要进一步研究AAS使用和冠状病毒感染之间的相互作用,特别是在运动员中.
科学领域:
- 运动医学 运动医学
- 免疫学 免疫学 免疫学
- 公共卫生 公共卫生
背景情况:
- COVID-19大流行暴露了医疗保健系统的脆弱性,并突出了公共卫生措施对社会活动的影响.
- 类固醇类固醇 (AAS) 是合成的类似物,用于性能和审美增强,并可能对免疫功能产生不良影响.
- 有限的研究存在于AAS使用和COVID-19结果之间的特定相互作用.
研究的目的:
- 审查使用类固醇类固醇 (AAS) 对感染SARS-CoV-2 (COVID-19) 的个体的潜在影响.
- 突出AAS的免疫系统改变效应及其加剧COVID-19相关风险的潜力.
- 讨论对运动员和从事体操等活动的个人的影响.
主要方法:
- 文献综述,重点关注AAS对免疫系统的影响.
- 分析AAS副作用与COVID-19病理生理学之间的潜在相互作用.
- 对包括运动员在内的弱势群体的风险的审查.
主要成果:
- 使用AAS可能会导致心血管,肝脏,脏和精神问题,这些问题可能会在COVID-19患者中放大.
- AAS具有免疫调节特性,可能会损害身体对SARS-CoV-2等病毒感染的反应.
- 运动员和健美运动员被确定为关键人群,由于AAS滥用普遍存在风险.
结论:
- 使用AAS存在重大健康风险,可能会因COVID-19感染而加剧.
- 在病毒大流行的背景下,AAS的免疫降低效应需要进一步调查.
- 公共卫生战略应考虑与AAS滥用相关的风险,特别是关于传染病结果的风险.
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