超声波测定便宽度:儿童膀和肠道功能障碍管理的客观指标
Tanner Hoppman1, Takahiro Ouchi2, Yiqing Dong3
1Vanderbilt University, Nashville, TN.
Urology
|January 4, 2024
概括
超声波测定便宽度 (SDFW) 有效地预测了标准泌尿疗法 (SU) 治疗膀和肠道功能障碍 (BBD) 的儿童的症状改善. 这一客观测量有助于评估治疗成功,即使在没有初始肠道问题的患者中也是如此.
科学领域:
- 儿科泌尿外科 儿科泌尿外科
- 胃肠病学 胃肠病学
- 诊断成像 诊断成像 诊断成像
背景情况:
- 膀和肠道功能障碍 (BBD) 在儿童中很常见,通常用标准泌尿疗法 (SU) 进行治疗.
- 在BBD中评估治疗反应可能是主观的,需要客观的标记.
- 超声波测定便宽度 (SDFW) 已成为一个潜在的客观指标.
研究的目的:
- 评估SDFW和儿童BBD患者接受SU的症状改善之间的相关性.
- 确定SDFW是否可以作为BBD治疗成功的客观衡量标准,包括没有初始肠道投诉的病例.
主要方法:
- 对200名儿科BBD患者进行了回顾性分析,他们接受了至少3个月的SU治疗.
- 根据国际儿童节制协会的指导方针,症状改善被分类为完全,部分或没有反应.
- 统计分析包括非参数ANOVA和t测试,以比较SDFW跨响应组和其他临床因素.
主要成果:
- 在较小的SDFW和更好的症状改善之间发现了统计学上显著的相关性 (P=.0001).
- 完全反应的患者平均SDFW为2.6厘米,而3.1厘米 (部分) 和3.3厘米 (无反应).
- 违规与较大的SDFW有关 (3.7厘米与3.1厘米,P=.0001),而VUR,UTI,PT和药物治疗没有显著影响便宽度.
结论:
- SDFW是一种可靠的客观参数,用于评估儿童BBD患者的治疗成功.
- 可以使用SDFW来监测治疗结果,即使在没有初始胃肠道症状的儿童中也是如此.
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