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Updated: Jul 6, 2025

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西诺因通过促进CRMP2的酸化和核转位来改善纤维细胞样同胞细胞功能障碍

Jie Yu1, Song Wang2, Si-Jia Chen2

  • 1The Second Affiliated Hospital of Zhejiang Chinese Medical University, Xinhua Hospital of Zhejiang Province, Hangzhou, 310053, China; College of Basic Medical Science, Key Laboratory of Neuropharmacology and Translational Medicine of Zhejiang Province, Zhejiang Chinese Medical University, Hangzhou, 310058, China.

Journal of ethnopharmacology
|January 4, 2024
PubMed
概括

西诺明因 (SIN) 通过减少关节炎症和疼痛来缓解类风湿性关节炎 (RA). 它通过调节纤维细胞样同胞细胞 (FLS) 中的CRMP2 T514酸化来实现这一目标,抑制炎症性细胞因子的释放,并抑制异常细胞入侵和迁移.

关键词:
在CRMP2中使用CRMP2.纤维细胞类同胞细胞类似于纤维细胞.核转位是指核转位.类风湿性关节炎 类风湿性关节炎 类风湿性关节炎这就是"sinomenine".

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