在COVID-19住院后的家庭氧气:来自多中心OXFORD研究的结果
Michael B Freedman1, Yoo Jin Kim2, Ramandeep Kaur2
1Drs Freedman and Kaul are affiliated with Division of Pulmonary, Critical Care, Sleep, and Allergy, Department of Medicine, University of Illinois Chicago, Chicago, Illinois; and Medical Service, Jesse Brown Veterans Affairs Medical Center, Chicago, Illinois. Drs Kim, Labedz, and Taylor and Ms Ziauddin are affiliated with Division of Pulmonary, Critical Care, Sleep, and Allergy, Department of Medicine, University of Illinois Chicago, Chicago, Illinois. Drs Kaur and Vines and Mr Rintz are affiliated with Division of Respiratory Care, Department of Cardiopulmonary Sciences, Rush University, Chicago, Illinois. Dr Jain is affiliated with Medical Service, Jesse Brown Veterans Affairs Medical Center, Chicago, Illinois; and Division of Hospital Medicine, Department of Medicine, Northwestern University, Chicago, Illinois. Dr Adegunsoye is affiliated with Section of Pulmonary Critical and Critical Care, Department of Medicine, University of Chicago, Chicago, Illinois. Dr Chung and Ms DeLisa are affiliated with Office of Population Health Sciences, University of Illinois Hospital and Health Sciences System, Chicago, Illinois. Ms Gardner is affiliated with Research Service, Jesse Brown Veterans Affairs Medical Center, Chicago, Illinois. Drs Gordon and Khouzam are affiliated with Medical Service, Jesse Brown Veterans Affairs Medical Center, Chicago, Illinois; and Academic Internal Medicine and Geriatrics, Department of Medicine, University of Illinois Chicago, Chicago, Illinois. Drs Greenberg and Mokhlesi are affiliated with Division Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, Rush University, Chicago, Illinois. Dr Rubinstein is affiliated with Division of Pulmonary, Critical Care, Sleep, and Allergy, Department of Medicine, University of Illinois Chicago, Chicago, Illinois; Medical Service, Jesse Brown Veterans Affairs Medical Center, Chicago, Illinois; and Research Service, Jesse Brown Veterans Affairs Medical Center, Chicago, Illinois. Drs Gerald and Krishnan are affiliated with Division of Pulmonary, Critical Care, Sleep, and Allergy, Department of Medicine, University of Illinois Chicago, Chicago, Illinois; and Office of Population Health Sciences, University of Illinois Hospital and Health Sciences System, Chicago, Illinois. mfreed2@uic.edu.
大约四分之一的住院COVID-19患者需要家庭氧气,即使有效的治疗方法已经可用. 对于降低家庭氧气需求的策略,需要进一步的研究.
科学领域:
- 肺部医学 肺部医学
- 传染性疾病 传染性疾病
- 关键的护理关键的护理
背景情况:
- 在有效治疗之前,在COVID-19大流行早期的住院治疗中,家庭使用氧气是常见的.
- 在经过验证的治疗方法建立后,人们对住院后的家庭氧气需求知之甚少.
研究的目的:
- 在可用基于证据的治疗方法后,调查住院COVID-19患者的家庭氧气使用的流行率和预测因素.
主要方法:
- 在2020年10月至2021年9月期间,对517名因COVID-19住院的患者进行了回顾性,多中心的队列研究.
- 从电子健康记录中提取的数据,包括人口统计,并发病,治疗和60天出院后的结果.
- 使用世界卫生组织COVID-19临床进展量表来定义严重疾病.
主要成果:
- 26%的患者在家用氧气上出院.
- 家庭氧气的预测因素包括年龄较大,BMI较高,糖尿病,严重的COVID-19和系统性皮质类固醇使用.
- 高血压与降低家庭氧气需求有关.
- 在出院后的60天内,有记录的脉冲氧计患者中有46%的患者停止了家庭氧气.
结论:
- 住院后的COVID-19幸存者在家处方氧气仍然很常见,尽管已建立有效的治疗方法.
- 需要基于证据的策略来尽量减少这些患者的家庭氧气需求.
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