口腔微生物群的酸盐降低能力在牙周炎中受损:对全身氧化可用性的潜在影响
Bob T Rosier1, William Johnston2,3, Miguel Carda-Diéguez1
1Department of Genomics and Health, FISABIO Foundation, Center for Advanced Research in Public Health, Valencia, Spain.
International journal of oral science
|January 4, 2024
概括
牙周炎损害了口腔微生物群的酸盐降低能力 (NRC),这对于氧化生产至关重要. 治疗恢复了NRC,这表明口腔健康影响系统氧化的可用性.
科学领域:
- 微生物学 微生物学
- 口腔健康 口腔健康
- 心血管健康 心血管健康
背景情况:
- 口腔微生物群将酸盐减少为酸盐,形成氧化,这有利于心脏代谢健康.
- 减少酸盐的细菌与牙周健康有关,但牙周炎对酸盐减少能力 (NRC) 的影响尚不清楚.
研究的目的:
- 研究牙周炎如何影响口腔微生物群的NRC.
- 为了评估经过牙周治疗后的NRC变化.
主要方法:
- 分析了来自五个国家的牙周炎患者和健康个体的16S rRNA测序数据.
- 在42名患者的牙周治疗前后测量了体外唾液NRC,与15名健康对照进行了比较.
主要成果:
- 与健康个体相比,牙周炎患者的酸盐减少细菌显着较低.
- 唾液NRC在牙周炎患者中减少,但在治疗后90天恢复到健康水平.
- 在治疗后,下减少酸盐的细菌增加,与牙周炎相关的细菌有负相关性.
结论:
- 牙周炎会损害口腔微生物群的NRC,可能会限制从酸盐中获得的氧化.
- 牙周治疗可以恢复口腔NRC,突出口腔健康和全身氧化物可用性之间的联系.
- 需要进一步的研究来探索牙周炎中受损的NRC对全身健康的影响.
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