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Updated: Jul 6, 2025

Alveolar Macrophage Phagocytosis and Bacteria Clearance in Mice
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库林5通过调节膜巨细胞抗病毒免疫力来驱动实验性喘恶化

Haibo Zhang1,2,3, Keke Xue1,2,3, Wen Li1,2,3

  • 1Shanghai Frontiers Science Center of Drug Target Identification and Delivery, School of Pharmaceutical Sciences, Shanghai Jiao Tong University, 200240, Shanghai, P. R. China.

Nature communications
|January 4, 2024
PubMed
概括

与病毒感染相关的喘恶化会随着Cullin5 (CUL5) 水平的提高而恶化. 减少CUL5可以提高抗病毒免疫力,减轻小鼠模型中的肺炎和喘严重程度.

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