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泰米斯是SHP1的基质和基激活剂,在T细胞发育过程中发挥双重作用

Jiali Zhang1,2,3, Zhenzhou Jiang1, Xueyuan Zhang1,4

  • 1School of Life Science and Technology, ShanghaiTech University, Shanghai, China.

Nature structural & molecular biology
|January 4, 2024
PubMed
概括

蛋白质THEMIS通过Tyr34的酸化来调节,影响CD4 T细胞的发育. 这种酸化控制T细胞受体信号传递,但THEMIS在T细胞扩张中也有其他作用.

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