第二信使2'3'-循环GMP-AMP (2'3'-cGAMP):细胞在癌症进展中的自主和非自主作用

Xiao-Yu Ma1,2,3, Man-Man Chen1,2,3, Ling-Hua Meng4,5,6

  • 1Division of Anti-tumor Pharmacology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 501 Haike Road, Shanghai, 201203, China.

PubMed
概括

细胞质DNA触发了cGAS-cGAMP-STING通路,这对免疫非常重要. 这种途径也会影响癌症的进展,为癌症治疗提供新的治疗点.

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