中国老年人中休息心率与认知衰退之间的关联:一项纵向队列研究
Zhaoyin Ma1,2, Yanlin Qu3,4, Haibo Ma1,5
1Department of Neurology, Jinan Central Hospital, Shandong University, Jinan, Shandong, People's Republic of China.
BMC geriatrics
|January 4, 2024
概括
较高的静止心率 (RHR) 与老年人的认知能力下降有关,特别是与身体不活动相结合时. 监测RHR和促进身体活动可能有助于预防认知能力下降.
科学领域:
- 老年学是一门学科.
- 心脏病学 心脏病学
- 神经学 神经学
背景情况:
- 在最老的老年人中,认知功能轨迹尚未得到充分理解.
- 休息心率 (RHR) 和认知能力下降之间的联系受到争论.
研究的目的:
- 调查RHR和认知衰退之间的关系.
- 在老年人中识别不同的认知功能轨迹.
- 探索体力活动 (PA) 在这种关系中的改变作用.
主要方法:
- 隐性类增长混合模型被用于确定3109名参与者反复认知评估的认知轨迹.
- 根据RHR,参与者被分为五组.
- 后勤回归模型分析了RHR和认知衰退之间的关联,考虑到PA.
主要成果:
- 确定了三个认知轨迹:高稳定,中度下降和快速下降. 认知能力下降被定义为中等/快速下降.
- 较高的RHR (≥70bpm) 与认知能力下降的风险增加有关.
- 观察到RHR和PA之间的相互作用:较高的RHR仅在身体不活跃的个体中构成风险.
结论:
- 休息心率超过70次/分钟是认知能力下降的重要危险因素.
- 身体活动改变了与较高RHR相关的认知衰退风险.
- 针对身体不活跃,RHR高的老年人的干预措施对于预防认知衰退至关重要.
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