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Updated: Jul 6, 2025

Loss- and Gain-of-function Approach to Investigate Early Cell Fate Determinants in Preimplantation Mouse Embryos
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Loss- and Gain-of-function Approach to Investigate Early Cell Fate Determinants in Preimplantation Mouse Embryos

Published on: June 6, 2016

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COUP-TFII调节了早期的双潜性淋巴体信号传递和对卵巢原始体的承诺

Lucas G A Ferreira1,2, Marina M L Kizys1, Gabriel A C Gama1

  • 1Laboratory of Molecular and Translational Endocrinology (LEMT), Endocrinology Division, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil.

Cell & bioscience
|January 4, 2024
PubMed
概括

转录因子COUP-TFII (NR2F2) 对于维持卵巢发育至关重要,因为它通过保持早期支持性腺细胞 (ESGCs) 的多能状态来维持卵巢发育. 损害NR2F2功能可能导致46,XX个体的丸发育.

关键词:
46,XX DSD DSD 的时间两个假设性腺体.在COUP-TFIIII中,我们可以性发展性发展性发展支持性腺细胞的支持性腺细胞

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Whole Ovary Immunofluorescence, Clearing, and Multiphoton Microscopy for Quantitative 3D Analysis of the Developing Ovarian Reserve in Mouse

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