从1990年到2019年,全球,区域和国家对中耳炎的负担:基于人口的研究
Yan Jin1,2, Xue Yang3,2, Hao Sun4,2
1Department of Emergency, The First Hospital of China Medical University, Shenyang, China.
Ear and hearing
|January 5, 2024
概括
由于疫苗接种,全球中耳炎的负担有所减少,但在中等SDI国家和特定地区的发病率正在上升. 持续监测对于管理这种常见的儿童疾病至关重要.
科学领域:
- 流行病学 流行病学
- 全球健康 全球健康
- 疫苗学 疫苗学 疫苗学
背景情况:
- 中耳炎是早期听力损失的主要原因.
- 用肺炎球菌合疫苗 (PCV-7,PCV-13) 接种疫苗影响了中耳炎的发生率.
- 关于近期中耳炎趋势的数据在全球范围内有限.
研究的目的:
- 评估1990-2019年中耳炎流行,发病率,死亡率和DALYs的全球趋势.
- 根据年龄,性别和社会人口统计指数 (SDI) 分析这些趋势.
- 评估疫苗接种对中耳炎负担的影响.
主要方法:
- 利用了2019年全球疾病负担研究数据.
- 在全球范围内分析了流行率,发病率,死亡率和DALY率.
- 计算年均百分比变化 (AAPC) 和分析子组趋势.
主要成果:
- 全球中耳炎患病率,DALY和死亡率呈现持续下降 (1990-2019).
- 发生率在PCV-7引入后 (2000-2009年) 急剧下降,并继续下降 (2010-2019年).
- 2019年的最高发病率在1-4岁儿童中;中等SDI国家显示出最大的发病率增加.
结论:
- 全球疫苗接种工作成功地减少了中耳炎的DALY和死亡率.
- 采用PCV-7和PCV-13导致中耳炎发病率大幅下降.
- 对中耳炎的持续流行病学监测对于监测趋势和耐药性模式至关重要.
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