关于结肠直肠癌心血管并发症的回顾性临床研究
Ting Yin1, Jianqi Yang2, Xiaojing Liu3
1Department of Oncology, Northern Jiangsu People's Hospital Affiliated to Yangzhou University, 225000 Yangzhou, Jiangsu, China. dating1220@163.com.
The heart surgery forum
|January 5, 2024
概括
心血管并发症在结肠直肠癌 (CRC) 患者中很常见,尤其是患有高LDL-C或CRP的老年人. 建议定期进行心脏监测,以对抗CRC.
科学领域:
- 心脏病学 心脏病学
- 在瘤学瘤学.
- 流行病学 流行病学
背景情况:
- 结肠直肠癌 (CRC) 是一个重要的全球健康问题.
- 心血管并发症是癌症患者的主要并发症.
- 了解这些风险对于全面的患者护理至关重要.
研究的目的:
- 为了确定患有结直肠癌的患者心血管并发症的发生率.
- 确定与这些并发症相关的关键风险因素.
- 为CRC患者的临床管理策略提供信息.
主要方法:
- 一项回顾性队列研究,涉及2085名结肠直肠癌患者.
- 来自中国两家三级医院 (2015-2020年) 的数据.
- 考克斯比例危险回归分析用于识别风险因素.
主要成果:
- 15.8%的CRC患者经历了心血管并发症.
- 在60岁以上的患者,高LDL-C,高CRP以及接受化疗/放射治疗的患者中观察到风险增加.
- 在患有并发症的患者中发现氧化应激标记 (MDA) 和抗氧化剂标记 (SOD,GPx) 的升高和降低.
结论:
- 心血管并发症是结直肠癌患者的一个重大问题.
- 老年,高的LDL-C和高的CRP是关键的危险因素.
- 建议对CRC患者进行常规心血管监测.
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