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Updated: Jul 6, 2025

The Soft Agar Colony Formation Assay
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通过通过RARα降低WNT4的调节,WYC-209抑制了GC恶性进展

Zhenyuan Qian1, Wenfa Lin2, Xufan Cai2

  • 1General Surgery, Cancer Center, Department of Gastrointestinal and Pancreatic Surgery, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, Hangzhou, Zhejiang, China.

Cancer biology & therapy
|January 5, 2024
PubMed
概括

通过抑制Wnt家族4 (WNT4) 成员的表达,WYC-209显示出对胃癌 (GC) 的强有力的抗癌作用. 这种机制涉及视网膜酸受体α (RARα) 与WNT4促进体结合,提供了一个新的治疗途径.

关键词:
在 GC GC 中.这是一个罕见的RARα.这就是WNT4的原因.在WYC-209中.合成的视网类物质.

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