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Murine Skin Transplantation
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通过转移体克服皮肤障碍:机遇,挑战和应用
Bhupendra Dixena1, Rashmi Madhariya1, Anupama Panday1
1Department of Pharmacy, Guru Ghasidas Vishwavidyalaya (A Central University), Bilaspur, (C.G.) 495009, India.
Current drug delivery
|January 5, 2024
概括
转移体提供增强的皮肤透通过皮肤递送药物,克服传统方法的局限性. 这些柔性囊泡有效地输送各种药物,改善治疗结果和患者的便利性.
科学领域:
- 制药科学 制药科学
- 药物输送系统 药物输送系统
- 纳米技术 纳米技术
背景情况:
- 透皮药物递送系统 (TDDS) 提供了诸如避免第一通代谢和持续药物释放等优势.
- 皮肤的透性是通过TDDS输送药物的一个主要挑战.
- 包括转移体在内的膀系统被探索以增强通过皮肤透.
研究的目的:
- 审查转移体的优点和局限性,以通过皮肤递送药物.
- 讨论通过转移体透到皮肤的机制.
- 要突出应用在提供抗癌,抗糖尿病,NSAIDs,草药,和通过皮肤免疫的应用.
主要方法:
- 用PubMed,谷歌学者和ScienceDirect进行的文献搜索.
- 审查现有关于转基因组制备和应用的研究.
- 对药物递送效率和皮肤透率的数据分析.
主要成果:
- 与其他膀系统相比,转移体表现出优越的灵活性和穿透皮肤.
- 它们有效地通过皮肤传递水性和水性药物.
- 针对抗癌药物,胰岛素,NSAIDs,草药和免疫的应用已经证明.
结论:
- 转移体是一个有前途的平台,用于先进的皮肤间药物输送.
- 它们的增强稳定性和透能力有助于系统性毒品运输.
- 转移体凝显示出改善通过皮肤给予药物的潜力.
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