由Trousseau综合征引起的脑梗塞与子宫癌相关
Motoko Kanno1, Mayu Yunokawa2,3, Atsushi Fusegi2
1Department of Gynecologic Oncology, The Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo, Japan. motoko.kanno@jfcr.or.jp.
Journal of gynecologic oncology
|January 5, 2024
概括
特鲁索综合征是一种与癌症相关的高凝血状态,在宫癌患者中很少发生. 当它出现时,它表明疾病已晚期,并且与非常短的生存时间有关.
科学领域:
- 在瘤学瘤学.
- 神经学 神经学
- 血液学 血液学 血液学
背景情况:
- 特鲁索综合征的特征是与癌症相关的高凝血性,往往导致预后不佳,特别是脑梗塞.
- 虽然在卵巢和子宫癌中有记录,但缺乏关于宫癌中特鲁索综合征的全面报告.
研究的目的:
- 在宫癌患者中全面总结特鲁索综合征的发生和特征.
- 调查特鲁索综合征在这种特定的妇科恶性瘤中的临床表现和预后影响.
主要方法:
- 在2014年1月至2021年12月期间诊断出宫癌患者的回顾性评估.
- 托鲁索综合征的定义是与癌症相关的动脉血栓形成,导致脑梗塞.
主要成果:
- 在1432名宫癌患者中,Trousseau综合征在6名 (0.4%) 患者中被发现.
- 这种综合症主要发生在患有晚期 (IIIC-IVB) 子宫癌和远程转移的患者中.
- 在Trousseau综合征发作后,中位生存时间非常短,平均为1个月.
结论:
- 与子宫癌相关的特鲁索综合征是一种罕见但严重的并发症.
- 它的发生意味着疾病已晚期,并且与生存率的快速下降有关,突出显示了预后不佳.
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