中国人乳和婴儿配方中的酸:度,分布和类型
Youping Lv1,2, Xinyue Wang3,4, Jiale Huang5
1State Key Laboratory of Vaccines for Infectious Diseases, Xiang An Biomedicine Laboratory, State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, National Innovation Platform for Industry-Education Integration in Vaccine Research, School of Public Health, Xiamen University, Xiamen, Fujian Province, 361102, People's Republic of China.
The British journal of nutrition
|January 5, 2024
概括
母乳含有比婴儿配方奶粉更多的酸 (SA),其度和类型各不相同. 人母乳是婴儿营养和发育中最喜欢的SA来源.
科学领域:
- 营养生物化学 营养生物化学
- 人类哺乳期研究研究
背景情况:
- 酸 (SA) 对于婴儿发育至关重要.
- 了解母乳与婴儿配方中的SA概况对于婴儿营养至关重要.
研究的目的:
- 为了比较乳母乳中的度,类型和分布在不同产后阶段与婴儿配方奶粉中的度,类型和分布.
- 评估对婴儿营养和配方奶粉生产的影响.
主要方法:
- 从产后2,7,30和90天的母亲那里收集了母乳样本.
- 在母乳和24种不同的婴儿配方奶粉中分析了SA特征.
- 与SA含量,结合 (寡糖与蛋白质) 和类型 (Neu5Ac, Neu5Gc) 的比较.
主要成果:
- 人类母乳中只含有Neu5Ac,在母乳中SA度最高,在3个月内下降.
- 大约68.776.1%的人类牛奶中的SA与寡糖化合物结合.
- 婴儿配方奶粉含有Neu5Ac和Neu5Gc,主要与蛋白质结合;配方奶粉养的婴儿可能获得较少的SA.
- 与婴儿配方相比,母乳在含量,动态,分布和类型方面是SA的优越来源.
结论:
- 人母奶为婴儿营养和发育提供了比目前可用的婴儿配方奶粉更有益的酸特征.
- 配方奶粉制造商应该考虑在母乳中发现的天然酸样本,以改进婴儿配方奶粉的设计.
相关概念视频
Polyprotic Acids
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Titration of a Polyprotic Acid
A polyprotic acid contains more than one ionizable hydrogen and undergoes a stepwise ionization process. If the acid dissociation constants of the ionizable protons differ sufficiently from each other, then the titration curve for such polyprotic acid generates a distinct equivalence point for each of its ionizable hydrogens. Therefore, titration of a diprotic acid results in the formation of two equivalence points, whereas the titration of a triprotic acid results in the formation of three...
Acid-Base Titration Curves
A titration curve is a plot of some solution property versus the amount of added titrant. For acid-base titrations, solution pH is a useful property to monitor because it varies predictably with the solution composition and, therefore, may be used to monitor the titration’s progress and detect its endpoint. Acid-base titration can be performed with a strong acid and a strong base, a strong acid and a weak base, or a strong base and a weak acid.
For a titration carried out for 25.00 mL of 0.100...
For a titration carried out for 25.00 mL of 0.100...
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The titration of a weak acid with a strong base results in the formation of water and the conjugate base of the acid. For instance, titrating acetic acid with sodium hydroxide leads to the formation of water and sodium acetate. A solution of acetic acid and sodium acetate constitutes a buffer whose relative concentration at different stages of the titration is indicated by the α values, which represent percentages of the weak acid and its conjugate base.
The α0 and α1 values represent the...
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Composition of Polyprotic Acid Solutions as a Function of pH
Polyprotic acids of the type H2M constitute two ionizable protons. As a result, on titration with a base, they exhibit two equivalence points in the titration curve. During titration, the species H2M, HM−, and M2− will be present in the solution at different points. The fractions of H2M, HM−, and M2− present at the various instances of the titration are denoted by α0, α1, and α2, respectively.
A graph with the alpha values is plotted against the volume of base added during titration. Here, a...
A graph with the alpha values is plotted against the volume of base added during titration. Here, a...
Acid–Base Titration: Overview
An acid-base titration is a technique used to determine the concentration of an unknown acid or base, using a titrant of known concentration–either a base for acid titration or an acid for base titration. The process involves gradually adding the titrant, leading to a predictable change in the pH of the solution. This change is plotted on a titration curve, showing how a solution's pH varies with the amount of titrant added. Such curves are instrumental in monitoring the titration's progress...


