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自闭症前期:儿科医生应该知道什么关于早期诊断自闭症的知识
1Department of Pediatric, Faculty of Medicine, Tanta University, Tanta 31511, Algahrbia, Egypt.
World journal of clinical pediatrics
|January 5, 2024
概括
早期发现自闭症谱系障碍 (ASD) 是至关重要的. 本综述探讨了用于早期自闭症风险识别的产前,新生儿和婴儿生物标志物,旨在提供客观的诊断工具.
科学领域:
- 神经发育障碍 神经发育障碍
- 儿科神经学 儿科神经学
- 生物标志物研究的研究.
背景情况:
- 自闭症谱系障碍 (ASD) 是一种复杂的神经发育状况,通常在儿童早期被诊断出来.
- 早期诊断对于有效的管理和改善结果至关重要.
- 目前对ASD的查方法有限,特别是在产前和新生儿中.
研究的目的:
- 审查早期自闭症检测的潜在生物标志物.
- 为了探索的概念的概念.
- 在自闭症前期.
- 在典型症状出现之前识别风险.
- 讨论ASD客观诊断工具的开发.
主要方法:
- 关于胎儿,新生儿和婴儿生物标志物的现有文献的综述.
- 对潜在的遗传,免疫,激素,代谢和放射性标记物的分析.
- 检查生物物理活动,行为概况和身体测量作为指标.
主要成果:
- 包括遗传和免疫因素在内的各种生物标志物显示出预测自闭症风险的潜力.
- 生物标志物阵列可能会导致ASD的客观诊断工具.
- 每个生物标志物都有独特的准确性和局限性.
结论:
- 开发一个全面的生物标志物阵列对于客观的ASD诊断和严重程度评估至关重要.
- 克服社区意识,获得工具和耻辱感等挑战对于改善早期检测至关重要.
- 需要对多种生物标志物的进一步研究,以加强对自闭症谱系障碍的早期识别和干预.
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