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在灵活的尿路透镜手术中,手术前的西洛多的疗效:一项随机对照研究
Hussein Shaher1, Ahmed Sebaey1, Ahmed Mahmoud Abd Albaky1
1Urology Department, Faculty of Medicine, Benha University, Benha, Egypt.
Arab journal of urology
|January 5, 2024
概括
作为阿尔法阻断剂的西洛多可缩短柔性尿道镜检查 (F-URS) 的手术时间,而不会影响无结石率或并发症. 这种辅助疗法在改善石头治疗手术效率方面表现有前途.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 内分泌病学 在内分泌病学.
- 药理学 药理学是指药理学的学科.
背景情况:
- 柔性尿道透视 (F-URS) 是一种常见的结石去除手术.
- 优化F-URS效率和患者结果是一个持续的临床挑战.
- 阿尔法阻塞剂已被探索,因为它们有可能促进石头的通过和手术程序.
研究的目的:
- 调查手术前的西洛多辛在改善灵活尿路透镜检查结果方面的疗效.
- 评估西洛多对手术阶段,手术时间和并发症的影响.
- 为了确定silodosin对F-URS后的无结石率 (SFR) 的影响.
主要方法:
- 一项前性随机受控试验,涉及106名接受F-URS的患者.
- 患者被分为两组:西洛多辛 (8毫克每天10天前程序) 和控制 (没有西洛多辛).
- 记录了关键指标,包括手术时间,接入的时间和尿管孔/膀进入的时间.
主要成果:
- 西洛多显著减少了手术时间,接入时间 (AAST),进入尿道孔时间 (ETUOT) 和进入膀时间 (ETBT).
- 虽然F-URS和激光时间在西洛多组略高,但这种差异在统计学上并不显著.
- 在西洛多和对照组之间,并发症率和无结石率 (SFR) 是可比的.
结论:
- 在手术前,西洛多的使用有效地缩短了柔性尿路透镜的手术时间.
- 西洛多作为一种有益的辅助疗法,提高了手术效率.
- 西洛多的使用不会对无石头率产生负面影响,也不会增加F-URS期间的并发症.
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