不同的三糖糖糖指数相关指标和牛皮之间的积极关联:来自NHANES的证据
Dawei Huang1,2, Rui Ma1,2, Xiaoyuan Zhong1,2
1Department of Dermatology, Shanghai Skin Disease Hospital, Tongji University School of Medicine, Shanghai, China.
这项研究发现,包括TyG-BMI,TyG-WC和TyG-WHtR在内的甘油三糖 (TyG) 指数指标与牛皮之间存在强烈联系. 高胰岛素抵抗 (IR) 与这种慢性炎症性皮肤疾病有显著的关联.
科学领域:
- 皮肤病学 皮肤病学
- 代谢综合征是代谢综合征的一种.
- 公共卫生 公共卫生
背景情况:
- 牛皮是一种具有全身影响的慢性炎症性皮肤疾病.
- 胰岛素抵抗 (IR) 与牛皮有关,但甘油三糖 (TyG) 指标的作用尚未完全理解.
研究的目的:
- 为了研究牛皮和三个与TyG相关的指标之间的关联:TyG-BMI,TyG-WHtR和TyG-WC.
- 探索这些代谢指标与牛皮的流行率之间的关系.
主要方法:
- 利用来自NHANES (2003-2006,2009-2014) 的9,291名成年人 (年龄在20-80岁) 的数据.
- 根据TyG-BMI,TyG-WC和TyG-WHtR将参与者分为五分之一.
- 采用多变量逻辑回归来评估相关性,报告赔率比率 (OR) 和95%置信区间 (CI).
主要成果:
- 在TyG-BMI,TyG-WC和TyG-WHtR和牛皮的较高五分位数之间发现了显著的积极关联.
- 在最初的模型中,TyG-WC显示了最高的OR值,而在调整后的模型中,TyG-BMI显示了显著的关系.
- 这些关联在各个子组和补充分析中保持一致.
结论:
- 与TyG相关的指标和牛皮之间存在稳定和强烈的积极关联.
- 这些发现表明,胰岛素抵抗性升高与牛皮的存在有显著联系.
- TyG-BMI,TyG-WC和TyG-WHtR可以作为评估牛皮风险的有价值指标.
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