在COVID-19流行病的第一年,新癌症诊断人数下降 - - 在波兰西部对350万个人的队列研究
Maciej Trojanowski1, Piotr Radomyski2,3, Witold Kycler4
1Greater Poland Cancer Registry, Greater Poland Cancer Centre, Poznan, Poland.
Frontiers in oncology
|January 5, 2024
概括
2020年,COVID-19大流行导致大波兰的新癌症诊断显著下降,男性的病例减少了20%,女性的病例减少了17%. 这种下降在男性骨髓瘤和女性骨癌中最为明显.
科学领域:
- 在瘤学瘤学.
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 随着COVID-19的流行,全球医疗保健系统发生了重大破坏.
- 预计癌症发病率,诊断和生存率将受到大流行影响.
- 了解这些影响对于公共卫生规划和癌症护理提供至关重要.
研究的目的:
- 评估大波兰在COVID-19大流行 (2020) 的最初一年癌症发病率的变化.
- 量化癌症诊断中由流行病引起的差距.
- 为了确定受流行病相关干扰影响最大的特定癌症类型.
主要方法:
- 对大波兰癌症登记处2010年至2020年间诊断的数据进行分析.
- 计算标准化发病率 (SIR) 和发病率差异 (IRD),以评估2020年的变化.
- 观察到的癌症病例与基于大流行前趋势的预期数字的比较.
主要成果:
- 2020年,总体癌症发病率大幅下降:与预期相比,男性的病例减少了20%,女性的病例减少了17%.
- 在男性的骨髓瘤 (SIR 0.59) 和女性的骨癌 (SIR 0.47) 中,最显著的减少.
- 在女性中观察到未指定部位癌症的意外增加 (SIR 1.19),可能表明诊断访问问题.
结论:
- 2020年,COVID-19大流行导致波兰大区的癌症诊断显著下降,男性的癌症诊断减少更大.
- 特定的癌症,如骨髓瘤和骨癌,受到不成比例的影响.
- 这些发现突显了癌症治疗途径的潜在破坏,以及持续监测和干预的必要性.
相关概念视频
01:21Cancer Survival Analysis
355
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
355
01:19Psychoneuroimmunology: Diabetes and Cancer
29
Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
29
02:49Cancer Therapies
7.7K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
7.7K