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计算研究表明,H463R突变如何将hKv1.5转化为失活状态

Ramisha A Rahman1, Bushra Zaman1, Mohammad Radid Khan1

  • 1Department of Mathematics & Physics, North South University, Plot # 15, Dhaka 1229, Bangladesh.

The journal of physical chemistry. B
|January 5, 2024
PubMed
概括

在Kv1.5通道中的H463R突变会产生能量屏障,破坏离子流,并可能导致心房动. 在Kv1.4通道的同等突变对离子导电的影响最小.

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