门排泄功能在性结肠炎患者的全方位切除术和阴道囊-门解剖术后:一个前性队列研究
Nikos Viazis1, Anastasios Manolakis2, Marina Vraka1
1Gastroenterology Department, Evangelismos-Polykliniki General Hospital, Athens.
European journal of gastroenterology & hepatology
|January 5, 2024
概括
整体直肠切除术与阴道袋-门解剖手术改善了肠道运动,并消除了性结肠炎患者的便失禁. 在手术后,门排便功能仍然具有能力.
科学领域:
- 胃肠病学 胃肠病学
- 结肠直肠手术 结肠直肠手术
- 生理学 生理学 生理学
背景情况:
- 整体直肠切除术 (TPC),其次是阴囊-门解剖 (IPAA) 是耐火性性结肠炎 (UC) 的标准手术治疗方法.
- 评估术后门排便功能和能力对于患者的治疗结果至关重要.
研究的目的:
- 预期评估UC患者在TPC加IPAA后的便功能和能力.
- 检查肠道排便频率的变化,便失禁和生活质量.
主要方法:
- 使用高分辨率直肠计量 (HR-ARM) 来评估门休息,挤压和推压.
- 进行了直肠感觉和直肠气球驱逐测试.
- 肠道排便频率,便失禁症状和IBDQ-32生活质量得分在手术前和后记录.
主要成果:
- 20名UC患者完成了这项研究.
- 平均肠道排便量显著下降,从10.1降至7.7 (P=0.01).
- 手术后便失禁得到缓解,IBDQ-32得分显著改善 (中位数为121.5至142.5).
- 门休息和挤压压力保持不变,表明门功能得到保护.
结论:
- 与IPAA一起的TPC可以改善UC患者的肠道运动模式和生活质量.
- 这种手术可以保持正常的门排便功能和能力.
- 在IPAA之后,HR-ARM是评估功能结果的宝贵工具.
相关概念视频
Inflammatory Bowel Disease V: Surgical Management
147
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Here are some common surgical interventions for IBD:
147
Assessment of the Rectum and Anus
224
Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
224
Inflammatory Bowel Disease I: Ulcerative Colitis
187
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
187
Drugs for Treatment of Ulcerative Colitis in IBD
144
Ulcerative colitis is a chronic inflammatory condition primarily affecting the colon and rectum. The primary drugs used in the treatment of ulcerative colitis are aminosalicylates. They exhibit anti-inflammatory and immunosuppressive properties. They modulate inflammatory mediators and inhibit the activity of nuclear factor κB (NF-κB). Aminosalicylates also reduce inflammation by inhibiting prostaglandin and leukotriene production and decreasing neutrophil chemotaxis and superoxide...
144
Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
88
Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
88
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
334
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
334


