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揭示烟斗吸烟与膀癌风险之间的关联:伊朗的一项多中心病例控制研究

Maryam Hadji¹, Hamideh Rashidian², Maryam Marzban^3,4

¹Health Sciences Unit, Faculty of Social Sciences, Tampere University, Tampere, Finland.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

|January 5, 2024

概括

水管吸烟与膀癌的风险更高有关,特别是那些不使用其他烟草产品的人. 这一发现强调了吸烟烟作为潜在的致癌物质,需要关注公共卫生.

科学领域:

在瘤学瘤学.
公共卫生公共卫生
流行病学流行病学

背景情况:

关于膀癌与水管吸烟之间的关联存在有限的数据.
水管吸烟是一个新兴的全球公共卫生问题.

研究的目的:

为了调查烟斗吸烟与膀癌症风险之间的关联.
为了检查与独家水管吸烟有关的风险.

主要方法:

使用了伊朗的IROPICAN数据库.
采用多变量逻辑回归,对吸烟,片使用和其他混因素进行调整.
分析了717例膀癌病例和3477例对照病例的数据.

主要成果:

与非吸烟者相比,仅吸烟水管的吸烟者显示出统计学上显著的风险增加 (OR = 1.78;95% CI,1.16-2.72).
在吸烟>2头/天 (OR = 2.25) 和开始使用年龄<20岁 (OR = 2.73) 的情况下,观察到最强的关联.
前吸烟者 (OR = 2.35) 的尿路膀癌症风险高于目前吸烟者 (OR = 1.52),尿路组织学相关性始终较高.

结论:

水管吸烟可能与膀癌的风险增加有关.
这种风险在没有接触过香烟和片的人群中显著.
水管吸烟已被证实是人类的致癌物,需要采取政策行动.

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