评估和管理的肝硬化患者与脑病变
H Kibble1,2, Debbie L Shawcross1,2
1Institute of Liver Studies, School of Immunology and Microbial Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK.
United European gastroenterology journal
|January 5, 2024
概括
肝脑病 (HE) 是肝损伤的严重并发症,表现为认知问题和昏迷. 早期肝移植转诊对于有肝硬化症的合格患者至关重要.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 胃肠病学 胃肠病学
- 神经学 神经学
背景情况:
- 肝脑病变 (HE) 是急性和慢性肝损伤的严重并发症,增加死亡风险.
- HE呈现为神经心理异常的一系列,从微妙的认知缺陷到昏迷.
- 虽然氨的作用是已知的,但肠道微生物群,炎症和感染越来越多地被认为是肝硬化中的HE驱动因素.
研究的目的:
- 审查肝硬化患者肝脑病变 (HE) 的实用性评估.
- 介绍目前的证据基础,用于治疗肝硬化患者的最佳治疗实践.
主要方法:
- 这是一个复习文章.
- 它综合了有关高等教育评估和管理的当前证据.
主要成果:
- HE表示肝硬化严重程度,如果没有肝移植,预后不好.
- 建议符合条件的患者提前考虑进行肝移植.
- 管理策略侧重于务实评估和基于证据的实践.
结论:
- 肝脏脑病是肝脏疾病严重程度的关键指标.
- 对于符合条件的患者来说,及时对肝移植进行评估至关重要.
- 有效的管理依赖于准确的评估和当前的最佳实践.
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