[帕金森病和综合征的其他功能症状]
Kirsten E Zeuner1, Petra Schwingenschuh2
1Klinik für Neurologie, Universitätsklinikum Schleswig-Holstein, Christian-Albrechts-Universität Kiel, Arnold-Heller-Str. 3 Haus 41, 24105, Kiel, Deutschland. k.zeuner@neurologie.uni-kiel.de.
Der Nervenarzt
|January 5, 2024
概括
功能性运动障碍可以与帕金森病和综合征同时发生,使诊断复杂化. 早期发现对于有效的,多学科的治疗策略至关重要.
科学领域:
- 神经学 神经学
- 运动障碍 运动障碍
- 功能神经系统疾病 功能神经系统疾病
背景情况:
- 功能运动障碍 (FMDs) 可以与帕金森病 (PD) 或其他综合征一起出现.
- 在口病和有机运动障碍之间的差异诊断是具有挑战性的.
- 口病可能在已确定的PD之前或同时发生,影响PD患者的7%.
研究的目的:
- 突出诊断在将口病与有机运动障碍区分开来时的困难.
- 概述临床特征和诊断工具,用于识别患有PD或综合征的患者的口腔疾病.
- 强调准确诊断对于适当的治疗计划的重要性.
主要方法:
- 临床观察特征性症状,如功能性步态障碍和低声说话.
- 使用分心技术 (认知,运动,暗示) 诊断功能.
- 使用神经成像,如多巴胺输送器SPECT (123I FP-CIT SPECT; DaTSCANTM) 来区分功能性帕金森症和PD.
- 考虑到神经生理学研究,如加速计.
主要成果:
- 在PD中,功能性症状可能与更严重的有机症状表现在同一侧.
- 患者表现出慢慢自动化的日常任务,低声说话,和布拉迪基尼西亚在手指敲击时没有减少.
- 多巴胺载体SPECT可以帮助区分功能性帕金森症和PD.
- 分心机动和加速度计对于在有机震综合征中诊断功能性震非常有价值.
结论:
- 在患有PD或综合征的患者中,精确区分口疾病至关重要.
- 口病的存在需要一个独特的治疗方法.
- 有效的管理需要一个多学科的团队来解决这些患者的复杂需求.
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