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在左心房附属体关闭后短期抗血小板与抗凝剂治疗:系统性审查和元分析

Qiang Zhou¹, Xiang Liu², Zhi-Chun Gu³

¹Department of Clinical Pharmacy, Jinling Hospital, Medical School of Nanjing University, Nanjing, 210002, China.

Journal of thrombosis and thrombolysis

|January 5, 2024

概括

与抗血小板疗法 (APT) 相比,在左心房附带关闭 (LAAC) 后短期口服抗凝药 (OAC) 显著降低了与设备相关的血栓和全因死亡率. 直接口服抗凝剂 (DOAC) 单一治疗显示出比华法林或OAC加APT更好的结果.

科学领域:

心脏病学心脏病学
干预心脏病学干预心脏病学
药理学药理学是指药理学的学科.

背景情况:

左心房尾关闭 (LAAC) 是口服抗凝药的替代方案,用于预防心房的中风.
在LAAC后最佳的抗血栓治疗仍在争论中,有效性和安全性的平衡.

结论:

短期OAC似乎比LAAC之后的APT更有利,特别是在减少DRT和死亡率方面.
在LAAC后,DOAC单疗可能是首选的抗凝剂策略,而不是华法林或双疗法 (OAC + SAPT).
需要进一步的研究来优化LAAC后的抗血栓治疗方案.

关键词:

抗血小板治疗是一种抗血小板疗法.与设备相关的血栓.左心房附加的关闭关闭.口服抗凝治疗是一种治疗方法.

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