在主观认知衰退中,告知者报告的认知投诉与纵向认知衰退之间的关联 一项为期7年的纵向研究
Yuanyuan Liu1,2, Ning Su1,2, Wei Li1,2
1Department of Geriatric Psychiatry, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
概括
在有主观认知衰退的老年人中,Informant报告的记忆力下降预测了未来的认知障碍. 这项为期7年的研究强调了护理人员在识别有风险的个体方面的价值.
科学领域:
- 老年学是一门学科.
- 认知神经学 认知神经学
- 流行病学 流行病学
背景情况:
- 主观认知衰退 (SCD) 是认知障碍的早期阶段.
- 举报人报告的记忆力下降 (IMD) 可能表明进展的风险更高.
- 基于社区的纵向研究对于理解认知轨迹至关重要.
研究的目的:
- 为了确定SCD的老年人IMD的预测值.
- 在7年的时间内评估IMD和认知衰退之间的关联.
- 识别有发展轻度认知障碍 (MCI) 或痴呆症的风险的个人.
主要方法:
- 一项为期7年的基于社区的队列研究包括90名患有SCD的参与者.
- 人口统计数据和神经心理测试得分在基线和随访时被收集.
- 后勤回归模型分析了基线IMD在7年的预测能力.
主要成果:
- 41%的SCD参与者报告IMD.
- IMD组表现出更多的抑郁症状和较低的基线认知分数 (MoCA,数字跨度,WAIS-PC).
- 54%的IMD组进展为MCI或痴呆症,而非IMD组的这一比例为22.6% (OR=3.361,p=0.028).
结论:
- 患有IMD的SCD个体表现出较差的认知能力和更高的进展到认知障碍的可能性.
- 对记忆衰退的知情感知对于识别有风险的个体是有价值的.
- IMD是老年人长期认知能力下降的重要预测因素.
相关概念视频
Cognitive Development During Adulthood
114
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
114
Longitudinal Research
12.0K
Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
12.0K
Longitudinal Studies
165
Longitudinal studies are also widely used in other medical and social science fields. For instance, in cardiovascular research, they can monitor patients' health over decades to identify risk factors for heart disease, such as high cholesterol or smoking, and evaluate the long-term effectiveness of preventive measures. Similarly, in mental health studies, researchers might follow individuals from adolescence into adulthood to understand the development and progression of conditions like...
165
Dementia
115
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
The progression of dementia is generally gradual....
115
Alzheimer's Disease: Overview
491
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
491
Cognitivism
1.4K
Cognitive psychology emerged as a significant field in the mid-20th century. It focused on understanding humans' internal mental processes. This approach emphasizes how people perceive, remember, think, and solve problems—elements critical to human cognition.
Previously dominated by behaviorism, which prioritized observable behaviors and largely ignored mental processes, psychology transformed in the 1950s. Cognitive psychologists argue that understanding how we think and process...
Previously dominated by behaviorism, which prioritized observable behaviors and largely ignored mental processes, psychology transformed in the 1950s. Cognitive psychologists argue that understanding how we think and process...
1.4K


