在中年社区人口中,睡眠规律,阻塞性睡眠呼吸暂停和高血压之间的相互关系
Kelly Sansom1,2,3, Amy Reynolds3, Daniel Windred4
1Centre for Sleep Science, School of Human Sciences, University of Western Australia, Perth, WA, Australia.
Sleep
|January 5, 2024
概括
不规律的睡眠模式增加了阻塞性睡眠呼吸暂停 (OSA) 和高血压的可能性. 将OSA与严重不规则的睡眠相结合显著增加高血压风险,这表明睡眠规律是关键的干预目标.
科学领域:
- 睡眠科学 睡眠科学
- 心血管健康 心血管健康
- 呼吸系统医学 呼吸系统医学
背景情况:
- 睡眠规律性,阻塞性睡眠呼吸暂停 (OSA) 和高血压之间的关系尚不清楚.
- 调查这些相互联系对于识别新的健康标志物和干预措施至关重要.
研究的目的:
- 为了检查睡眠规律与OSA之间的关联.
- 为了确定不规则的睡眠是否与高血压有关.
- 评估睡眠规律是否会改变OSA和高血压之间的关系.
主要方法:
- 六百二名成年人接受了OSA的多睡眠学和睡眠规律性 (睡眠规律性指数-SRI) 的手腕动图.
- 参与者被分为正常,轻度不规则或严重不规则的睡眠组.
- 后勤回归模型分析了SRI,OSA和高血压之间的关联,控制共变量.
主要成果:
- 与正常睡眠者相比,轻度和严重不规则的睡眠者患上OSA的几率明显更高.
- 在OSA和严重不规则的睡眠的组合呈现的高血压的最高几率.
- 对于患有OSA和正常或轻微不规则的睡眠模式的人来说,没有观察到高血压风险的增加.
结论:
- 睡眠不规则与OSA的患病率增加有关.
- 严重不规则的睡眠,与OSA结合,显著提高高血压的风险.
- 改善睡眠的规律性可能代表一个可修改的治疗目标管理高血压在患有OSA的个体.
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