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Updated: Jul 6, 2025

Investigation of RNA Synthesis Using 5-Bromouridine Labelling and Immunoprecipitation
09:59

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Published on: May 3, 2018

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通过将其结构化的mRNA与核酶向的嵌合体向其结构化的mRNA,降低内在无序的蛋白α-synuclein水平

Yuquan Tong1,2, Peiyuan Zhang1, Xueyi Yang1,2

  • 1Department of Chemistry, The Scripps Research Institute, Jupiter, FL 33458.

Proceedings of the National Academy of Sciences of the United States of America
|January 5, 2024
PubMed
概括

研究人员开发了Synucleozid-2.0和Syn-RiboTAC以准α-synuclein (α-synuclein) mRNA用于帕金森病 (PD) 治疗. 在PD模型中,Syn-RiboTAC有效降解α-synuclein mRNA,降低蛋白质水平并挽救基因表达.

关键词:
这是阿尔茨海默氏症.这是一个RNARNARNARNARNA.帕金森主义是帕金森主义.有针对性的降解降解目标.α-synuclein 是一种同核蛋白.

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