肢体特异性肌肉交感神经活动对冷压器测试的反应
Yasmine Coovadia1, Brittany K Schwende1, Chloe E Taylor2
1Cardiovascular Health and Autonomic Regulation Laboratory, McGill University, Montreal, Quebec, Canada.
Autonomic neuroscience : basic & clinical
|January 5, 2024
概括
冷压器测试 (CPT) 在刺激上肢或沉浸肢体时,会引起更大的肌肉交感神经活动 (MSNA) 反应. 这些发现突出了对寒冷暴露的同情反应的四肢依赖差异.
科学领域:
- 身体生理学 身体生理学
- 自主神经系统的自主神经系统
- 心血管监管 监管心血管系统
背景情况:
- 肌肉交感神经活动 (MSNA) 对等比运动的反应显示出肢体依赖的变化.
- 目前尚不清楚一种常见的生理压力因素 - - 寒冷压力测试 (CPT) - - 是否也会根据四肢参与引起不同的MSNA反应.
研究的目的:
- 调查CPT诱导的MSNA反应是否在受刺激 (受影响) 和非受刺激 (不受影响) 肢体之间有所不同.
- 为了测试MSNA在受刺激的下肢中比对侧下肢和上肢更大,这一假设.
主要方法:
- 在10名健康的年轻成年人中,使用微神经图测量了综合腹腔MSNA.
- 参与者接受了三个单独的3分钟的CPT,包括微神经图脚,相反的脚或相反的手的沉浸.
- 峰值MSNA和平均动脉压 (MAP) 被记录和分析.
主要成果:
- 当微神经扫描脚被浸泡时,MSNA反应明显高于相反的脚 (38比28次爆发/100hb,P<0.01).
- 在手浸泡时,MSNA反应比双脚浸泡时 (46 vs 38 和 28 爆发/100hb,P < 0.01) 更大.
- 与足 CPT 相比,手 CPT 中的 MAP 反应也较高 (99 与 96 mmHg 相比,P < 0.01).
结论:
- 由CPT诱导的MSNA反应是肢体依赖的.
- 上肢和沉浸四肢与下肢和/或非沉浸四肢相比,引发了更大的交感神经活动反应.
- 这些发现有助于理解在寒冷压力期间的神经血管控制.
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